Fasciola hepatica

Title: One-Health Approach to Study Human Fasciola hepatica Transmission and Inform Strategic Control (Copy 1)

Year Started: 2022

Cross sectional study including human, livestock, snails, and the environment to study the transmission of Fasciola hepatica in the highlands of Peru. Feces (human and livestock), serum (human), plasma (human), and PBMCs (human), tissue (snail), and water samples will be collected to study factors associated with transmission. We expect to include 1,500 children and adults and their farms (water bodies within them). We will study 4,800 livestock.



Access:
Open only through collaboration
Type:
Cross-sectional
Status:
In progress
Consent restrictions:
No restrictions


Associated Data Type Procurement Timeframe
Followup records 0 - 3 months
Freezer temperature logs 3 - 6 months
Survey data 0 - 3 months
Treatment records 0 - 3 months


Both sexes

Child (6 - 12 years)

101 - 500 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Microscopic Assessment % of Sample Set
Stool -85°C to -60°C Not applicable 75% -99%


Both sexes

Adolescent (12 - 18 years)

101 - 500 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Microscopic Assessment % of Sample Set
Stool -85°C to -60°C Not applicable 75% -99%


Both sexes

Young child (2 - 6 years)

101 - 500 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Microscopic Assessment % of Sample Set
Stool -85°C to -60°C Not applicable 75% -99%


Both sexes

Young adult (18 - 40 years)

101 - 500 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Microscopic Assessment % of Sample Set
Stool -85°C to -60°C Not applicable 75% -99%


Both sexes

Adult (> 40 years)

101 - 500 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Microscopic Assessment % of Sample Set
Stool -85°C to -60°C Not applicable 75% -99%


Both sexes

Young child (2 - 6 years)

101 - 500 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Microscopic Assessment % of Sample Set
Serum -85°C to -60°C Not applicable 51 - 75%


Both sexes

Child (6 - 12 years)

101 - 500 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Microscopic Assessment % of Sample Set
Serum -85°C to -60°C Not applicable 51 - 75%


Both sexes

Adolescent (12 - 18 years)

101 - 500 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Microscopic Assessment % of Sample Set
Serum -85°C to -60°C Not applicable 51 - 75%


Both sexes

Young adult (18 - 40 years)

101 - 500 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Microscopic Assessment % of Sample Set
Serum -85°C to -60°C Not applicable 51 - 75%


Both sexes

Young child (2 - 6 years)

101 - 500 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Microscopic Assessment % of Sample Set
Plasma (single spun) -85°C to -60°C Not applicable 75% -99%


Both sexes

Adolescent (12 - 18 years)

101 - 500 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Microscopic Assessment % of Sample Set
Plasma (single spun) -85°C to -60°C Not applicable 75% -99%


Both sexes

Young adult (18 - 40 years)

101 - 500 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Microscopic Assessment % of Sample Set
Plasma (single spun) -85°C to -60°C Not applicable 75% -99%


Both sexes

Adult (> 40 years)

101 - 500 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Microscopic Assessment % of Sample Set
Plasma (single spun) -85°C to -60°C Not applicable 75% -99%


Both sexes

Adolescent (12 - 18 years)

101 - 500 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Microscopic Assessment % of Sample Set
Isolated peripheral blood mononuclear cells (viable) Liquid nitrogen Not applicable 26 - 50%

Fasciola hepatica

Title: One-Health Approach to Study Human Fasciola hepatica Transmission and Inform Strategic Control (Copy 1) (Copy 1)

Year Started: 2022

Cohort study including human, livestock, snails, and the environment to study the transmission of Fasciola hepatica in the highlands of Peru. Feces (human and livestock), serum (human), plasma (human), and PBMCs (human), tissue (snail), and water samples will be collected to study factors associated with transmission. We expect to include 500 children and adults and their farms (water bodies within them). We will study 4,800 livestock.



Access:
Open only through collaboration
Type:
Cohort
Status:
Not-started
Consent restrictions:
Human genetic analysis restriction


Associated Data Type Procurement Timeframe
Followup records 0 - 3 months
Freezer temperature logs 3 - 6 months
Survey data 0 - 3 months
Treatment records 0 - 3 months


Both sexes

Child (6 - 12 years)

101 - 500 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Microscopic Assessment % of Sample Set
Stool -85°C to -60°C Not applicable 75% -99%


Both sexes

Adolescent (12 - 18 years)

101 - 500 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Microscopic Assessment % of Sample Set
Stool -85°C to -60°C Not applicable 75% -99%


Both sexes

Child (6 - 12 years)

101 - 500 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Microscopic Assessment % of Sample Set
Serum -85°C to -60°C Not applicable 51 - 75%


Both sexes

Adolescent (12 - 18 years)

101 - 500 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Microscopic Assessment % of Sample Set
Serum -85°C to -60°C Not applicable 51 - 75%


Both sexes

Adolescent (12 - 18 years)

101 - 500 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Microscopic Assessment % of Sample Set
Plasma (single spun) -85°C to -60°C Not applicable 75% -99%


Both sexes

Adolescent (12 - 18 years)

101 - 500 donors

Material Type Extraction Procedure Storage Temperature Preservation Type Microscopic Assessment % of Sample Set
Isolated peripheral blood mononuclear cells (viable) Liquid nitrogen Not applicable 26 - 50%